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KMID : 0375920070250010091
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Journal of Rehabilitation Science
2007 Volume.25 No. 1 p.91 ~ p.102
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The Review of Expression of GFAP in CNS Injury
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Ha Mi-Sook
Park Rae-Joon
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Abstract
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Purpose : The purpose of this study was to uderstand the glial fibrillary acidic protein through literature review about CNS injury.
Method : This is a western bolt analysis, immunocytochemical analysis and double immunofluorescence for glial fibrillary acidic protein were performed after CNS injury.
Result : The GFAP expression level in the gray matter increased in the early stage of injury. In contrast the GFAP expressoin level in the gray matter decreased in the late stage of injury.
Conclusion : The study of GFAP is the intermediate filament of the glial cells and useful as a marker for the astrocytes. Also, the upregulation of GFAP espression required various physical therapeutic approaches.
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